helb is a feedback inhibitor of dna end resection
Tkáč j xu g adhikary h young jtf gallo d escribano díaz c krietsch j orthwein a munro m sol w et al. In the repair of a conventional dsb 53bp1 both suppresses dna end resection and promotes cnhej although it is not a core cnhej factor 156 160 161 fig. Helb is a feedback inhibitor of dna end resection.
Hij is emeritus hoogleraar klinische biochemie en moleculaire biologie aan de universiteit van amsterdam emeritus wetenschappelijk directeur van het nederlands kanker instituut nki en het antoni van leeuwenhoekziekenhuis daar werkte hij tot eind 2016 nog als fulltime.
repair of dna double strand breaks
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genome maintenance by dna helicase b
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limiting the dna double strand break
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regulation of single strand annealing
