dna dependent rna polymerase
Gene expression begins with dna dependent rna polymerase rna polymerase catalyzing the transcription of specific mrna from one strand of a dna template. Cell identity and fate are determined by a cell s repertoire of expressed genes. In virus species with reverse transcriptase lacking dna dependent dna polymerase activity creation of double stranded dna can possibly be done by host encoded dna polymerase δ mistaking the viral dna rna for a primer and synthesizing a double stranded dna by similar mechanism as in primer removal where the newly synthesized dna displaces.
Binding of rna polymerase to dna occurs at specific sites called promoters and transcription begins adjacent to the promoter.

Dna dependent rna polymerase. The dna pkcs protein is a serine threonine protein kinase comprising a single polypeptide chain of 4 128 amino acids. The dna dependent rna polymerase binds to the promoter and catalyses the polymerization in the 5 to 3 direction on the template strand. It uses single strand dna to synthesize a complementary rna strand. Dna pkcs belongs to the phosphatidylinositol 3 kinase related kinase protein family.
A rna polymerase becomes associated transiently with initiation factor and binds to the promoter site on dna and initiates transcription. Transcription is regulated both during initiation and elongation of the rna chain. Gene expression is regulated at the level of dna dependent rna polymerases which make rna copies from dna templates through a process called transcription. Ans i role of dna dependent rna polymerase.
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