dnaリガーゼ atp

Dnaリガーゼ ディーエヌエーリガーゼ dna ligase は dna鎖の末端同士をリン酸ジエステル結合でつなぐ酵素である 生体内では主としてdna複製とdna修復に寄与している 一方 遺伝子工学で組換えdnaを作るために頻繁に利用されている ec番号は6 5 1 1 基質atp または6 5 1 2 基質nad. It also joins dna fragments with either cohesive or blunt term.

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slides show

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troubleshooting dna ligation in ngs library prep enseqlopedia

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brenda enzyme database

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http worthington biochem com dnat4l default html

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