bcr abl promotes the frequency of mutagenic single strand annealing dna repair
Bcr abl downregulates c jun expression by activating the pi3k akt pathway during chronic phase of chronic myeloid leukemia cml cp. This gene encodes a 190 kd nuclear phosphoprotein that plays a role in maintaining genomic stability and it also acts as a tumor suppressor. Devita hellman and rosenberg s cancer principles practice of oncology 11th edition.
Bcr abl promotes the frequency of mutagenic single strand annealing dna repair.



















































































